In what areas have you found that you benefit from listening to someone who's really smart about the decision you need to make?
Not a self-appointed expert, but someone with experience, patience and maturity, someone who's been educated in the field, practiced in it, someone who understands the history and the mechanics of what's on offer…
Certainly, most of us would agree that in areas like removing a tumor, investing a nest egg or even baking a loaf of bread, listening to these folks is the way to go. Ignoring all of them is foolhardy.
Sometimes, in our search for the new thing, we mistakenly grab the foolish thing instead. "I'm with stupid."
Challenging the status quo and going against all the the traditional rules of thumb is a great way to take a leap. But that sort of leap needs to be a portfolio play, part of a larger arc, not a matter of life and death, not the last spin of the wheel you're going to get if you're wrong.
[Worth noting that plenty of smart people shunned Semmelweis, Lovelace and Alan Kay. But not all of the smart people.]
By all means, take these intellectual risks. But not when you're skydiving. Being uninformed doesn't make you a renegade. It merely makes you uninformed.